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Magnafolate with Better Stability and Pharmacokinetics

2022-01-18

Recently, one test has been conducted between C Crystal Calcium 6S-5-Methyltetrahydrofolate (Magnafolate)I Crystal Calcium 6S-5-MTHF and Glucosamine Salt 6S-5-MTHF by Jinkang Pharma. From that you can see Magnafolate shows greater stability than I Crystal Calcium 6S-5-MTHF and Glucosamine Salt 6S-5-MTHF. In addition, Magnafolate is well absorbed and better utilized in SD rats in contrast to others. The relative bioavailability of Magnafolate was calculated to be 351% and 218% compared with I Crystal Calcium 6S-5-MTHF and Glucosamine Salt 6S-5-MTHF respectively. The results indicates that Magnafolate is a good supplement to folate.

We are pleased to inform you that the article "Improved Stability of a Stable Crystal Form C of 6S-5-Methyltetrahydrofolate Calcium Salt, Method Development and Validation of an LC–MS/MS Method for Rat Pharmacokinetic Comparison" has been published in Molecules and is available online:


PDF Version: https://www.mdpi.com/1420-3049/26/19/6011/pdf 


Magnafolate® ,the Manufacturers & Supplier of active folate.