Your body needs L-5-methylfolate rather than folate Folic acid, folate, L-5-methylfolate—it’s all the same right? Not quite. Your body needs methylfolate; the purest form of Vitamin B9.

What is L-5-Methylfolate? L-5-methylfolate is the biologically active form of vitamin B9. That means it is the form the human body can actually use in circulation.

Calcium L-5-methyltetrahydrofolate (L-5-MTHF-Ca; CAS No. 151533-22-1) is the calcium salt of L-5- methyltetrahydrofolic acid (L-5-MTHF), which is the predominant naturally occurring folate in foods.The regular marketed L-5- MTHF Ca purity is 97.5%,even though the standard is 95%-102%,meanwhile Magna......

Does the form of folate matter? The short answer: Yes. Folic acid is the form used in many supplements because it’s highly stable. The caveat? Once folic acid enters a cell, it needs to be converted into 6S-5-Methyltetrahydrofolate (MTHF) by several key enzymes before your body can use it. And up t......

How should we get right folate? The best dietary sources of natural folate include fresh fruits, leafy greens, yeast, and legumes, but these can easily be degraded during food prep and cooking; this means that those foods often become less nutritious sources of folate as soon as they’re manipulated......

Methylfolate can be quickly manufactured as a material that has both the 6S and 6R isomers (or L and D respectively).